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But set between these two is my favorite of the Cycladic Islands: Ios.

Exterior of Calilo

View of Calilo guest rooms, and main resort pool seen from one of the bridges that connect the main resort to the beach.Credit:Alessandra Amodio/Travel + Leisure

The five-star resort, opened in 2019, is the most recent addition to the Michalopoulos familys boutique collection.

Read on for my full review of Calilo.

Rooms with personal water features also have outdoor natural rock showers made of materials sourced from Ios.

Papas Beach , Ios Greece

Aerial view of Papas Beach.Alessandra Amodio/Travel + Leisure

Calilos multi-room suites, architecture, and design make it the perfect destination for the child-at-heart and families alike.

I think its important to have a place that stimulates you emotionally, Angelos Michalopoulos tellsTravel + Leisure.

(My favorite late-night in-room snack was chicken nuggets and potatoes with feta.)

Interior of Calilo

Thee Calilo property is filled with an assortment of water features and swings for guests to enjoy.Alessandra Amodio/Travel + Leisure

Here, the chef prepares a nine-course tasting menu, with each course inspired by a Cycladic island.

Opt for the wine pairing to experience some exceptional Greek wines.

Bring your group or join others for a wine tasting that explores Greece and Europe.

Calilo guest room

More adventurous guests can trek through Ios’s incredible and untouched landscapes.

My favorite activity was a private boat excursion.

This is where the Michalopoulos family truly shines.

Heart shaped pool suite at Calilo

I want to ensure that Ios is still successful 20 years from now," says Michalopoulos.

We believe we do not have to damage the earth to accomplish our dreams."

Environmental protection and sustainability are vital pillars of their family ethos and development.

Guest room pools at Calilo in Greece

Thus, the Elektra Olive Tree project was born.

Some of these trees are located here at Calilo.

Location

As the small island it is, Ios is best reached by water.

Plunge pools in Calilo guest room

If your trip allows it, I recommend flying into Santorini first.

The international airport accepts most direct or connecting flights, depending on your departure location.

Getting on one of the larger ferries is always better for those prone to seasickness.

Calilo guest room

It can sometimes take a little longer, but the ride can be much smoother.

Heart shaped pool suite at Calilo

Guest room pools at Calilo in Greece

Plunge pools in Calilo guest room

CHES at Calilo

View from the CHES dining terrace and the dish inspired by the island of Naxos.Alessandra Amodio/Travel + Leisure

Kalamos Beach and bay in Ios Greece

View of Kalamos Beach while sailing around the Greek island of Ios.Alessandra Amodio/Travel + Leisure

spa treatment rooms at Calilo

Interior of one of the spa treatment rooms at Calilo.Alessandra Amodio/Travel + Leisure

Olive tree at Calilo

The olive tree lining boardwalk down to the water.Alessandra Amodio/Travel + Leisure

Port of Ios

Sailboats and homes around the port of Ios.Alessandra Amodio/Travel + Leisure