See small towns and bustling cities by boat on a Mississippi River cruise.

you could access some of the nation’s iconic attractions and favorite cities right from the Mississippi River.

Here’s what you gotta know about Mississippi River boat cruises, from choice itineraries to popular stops.

A Viking river cruise on the Mississippi River

Credit: Rottet Studio/Courtesy of Viking

The company’s flagship, theAmerican Queen,is said to be the world’s biggest steamboat.

Several riverboats cruise this route, includingAmerican MelodyandAmerican Symphony, inaugurated in 2021 and 2022, respectively.

These sister vessels offer large rooms and suites with contemporary furnishings and an upscale feel.

Curving road along the Mississippi River near Brainerd, Minnesota in the fall.

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The interior of the Grand Suite on the American Melody

Courtesy of American Cruise Lines

The American Melody on the Mississippi River

Courtesy of American Cruise Lines

Interior of the Lounge on board the Viking Mississippi River Cruise

Rottet Studio/Courtesy of Viking